ARHGAP9 Polyclonal Antibody

    • Catalog No.:YT0320
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • ARHGAP9
      • Gene Name:
      • ARHGAP9
      • Protein Name:
      • Rho GTPase-activating protein 9
      • Human Swiss Prot No:
      • Q9BRR9
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human RHG9. AA range:220-269
      • Specificity:
      • ARHGAP9 Polyclonal Antibody detects endogenous levels of ARHGAP9 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • ARHGAP9;Rho GTPase-activating protein 9;Rho-type GTPase-activating protein 9
      • Observed Band(KD):
      • 90kD
      • Background:
      • This gene encodes a member of the Rho-GAP family of GTPase activating proteins. The protein has substantial GAP activity towards several Rho-family GTPases in vitro, converting them to an inactive GDP-bound state. It is implicated in regulating adhesion of hematopoietic cells to the extracellular matrix. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
      • Function:
      • function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of hematopoietic cells to the extracellular matrix.,similarity:Contains 1 PH domain.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 1 WW domain.,tissue specificity:Predominantly expressed in peripheral blood leukocytes, spleen, and thymus.,
      • Subcellular Location:
      • cytosol,
      • Expression:
      • Predominantly expressed in peripheral blood leukocytes, spleen, and thymus.
      • Products Images
      • Western blot analysis of lysates from LOVO cells, using RHG9 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from COLO205 cells using RHG9 antibody.
      • Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).