Ameloblastin Polyclonal Antibody

    • Catalog No.:YT0209
    • Applications:WB;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • Ameloblastin
      • Gene Name:
      • AMBN
      • Protein Name:
      • Ameloblastin
      • Human Gene Id:
      • 258
      • Human Swiss Prot No:
      • Q9NP70
      • Mouse Swiss Prot No:
      • O55189
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human Ameloblastin. AA range:275-324
      • Specificity:
      • Ameloblastin Polyclonal Antibody detects endogenous levels of Ameloblastin protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • AMBN;Ameloblastin
      • Observed Band(KD):
      • 48kD
      • Background:
      • This gene encodes the nonamelogenin enamel matrix protein ameloblastin. The encoded protein may be important in enamel matrix formation and mineralization. This gene is located in the calcium-binding phosphoprotein gene cluster on chromosome 4. Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect. [provided by RefSeq, Aug 2011],
      • Function:
      • disease:Defects in AMBN are found in patients with ameloblastomas.,function:Involved in the mineralization and structural organization of enamel.,similarity:Belongs to the ameloblastin family.,tissue specificity:Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel.,
      • Subcellular Location:
      • Secreted, extracellular space, extracellular matrix.
      • Expression:
      • Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel.
      • Products Images
      • Western blot analysis of lysates from HeLa cells, using Ameloblastin antibody.