• Target：
• ABCD4

• Fields：
• >>ABC transporters;>>Peroxisome

• Gene Name：
• ABCD4

• Protein Name：
• ATP-binding cassette sub-family D member 4

• Human Gene Id：
• 5826

• Human Swiss Prot No：
• O14678

• Mouse Gene Id：
• 19300

• Mouse Swiss Prot No：
• O89016

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human ABCD4. AA range:111-160

• Specificity：
• ABCD4 Polyclonal Antibody detects endogenous levels of ABCD4 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• ABCD4;PXMP1L;ATP-binding cassette sub-family D member 4;PMP70-related protein;P70R;Peroxisomal membrane protein 1-like;PXMP1-L;Peroxisomal membrane protein 69;PMP69

• Observed Band(KD)：
• 70kD

• Background：
• The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxi

• Function：
• similarity:Belongs to the ABC transporter family. ALD subfamily.,similarity:Contains 1 ABC transmembrane type-1 domain.,similarity:Contains 1 ABC transporter domain.,subunit:Homodimer or heterodimer .,tissue specificity:Ubiquitous.,

• Subcellular Location：
• Endoplasmic reticulum membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Targeted by LMBRD1 lysosomal chaperone to the lysosomal membrane. .

• Expression：
• Ubiquitous.

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