ABCA6 Polyclonal Antibody

    • Catalog No.:YT0043
    • Applications:WB;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • ABCA6
      • Fields:
      • >>ABC transporters
      • Gene Name:
      • ABCA6
      • Protein Name:
      • ATP-binding cassette sub-family A member 6
      • Human Swiss Prot No:
      • Q8N139
      • Mouse Swiss Prot No:
      • Q8K441
      • Immunogen:
      • Synthesized peptide derived from ABCA6 . at AA range: 1180-1260
      • Specificity:
      • ABCA6 Polyclonal Antibody detects endogenous levels of ABCA6 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • ABCA6;ATP-binding cassette sub-family A member 6
      • Observed Band(KD):
      • 185kD
      • Background:
      • The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis. [provided by RefSeq, Jul 2008],
      • Function:
      • developmental stage:Expressed in fetal kidney, lung and liver.,function:Probable transporter which may play a role in macrophage lipid homeostasis.,induction:Up-regulated during monocyte differentiation into macrophages. Down-regulated by cholesterol loading of macrophages.,similarity:Belongs to the ABC transporter family. ABCA subfamily.,similarity:Contains 2 ABC transporter domains.,tissue specificity:Widely expressed with higher expression in liver.,
      • Subcellular Location:
      • Golgi apparatus membrane ; Multi-pass membrane protein .
      • Expression:
      • Widely expressed with higher expression in liver.
      • Products Images
      • Western Blot analysis of various cells using ABCA6 Polyclonal Antibody