NFκB-p105 (phospho Ser907) Polyclonal Antibody

    • Catalog No.:YP0184
    • Applications:WB,IHC-p,IP,ELISA
    • Reactivity:Human
    • Description
    • Gene Name:
    • NFKB1
    • Protein Name:
    • Nuclear factor NF-kappa-B p105 subunit
    • Human Gene Id:
    • 4790
    • Human Swiss Prot No:
    • P19838
    • Mouse Swiss Prot No:
    • P25799
    • Immunogen:
    • The antiserum was produced against synthesized peptide derived from human NF-kappaB p105/p50 around the phosphorylation site of Ser907. AA range:874-923
    • Specificity:
    • Phospho-NFκB-p105 (S907) Polyclonal Antibody detects endogenous levels of NFκB-p105 protein only when phosphorylated at S907.
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/20000. Not yet tested in other applications.
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Other Name:
    • NFKB1; Nuclear factor NF-kappa-B p105 subunit; DNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
    • MolecularWeight(Da):
    • 105356
    • Observed Band(KD):
    • 110
    • Background:
    • NFKB1 encodes a 105 kD protein (nuclear factor kappa B subunit 1) which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-spe
    • Function:
    • negative regulation of transcription from RNA polymerase II promoter, regulation of cytokine product
    • Products Images
    • Western Blot analysis of various cells using Phospho-NFκB-p105 (S907) Polyclonal Antibody diluted at 1:2000
    • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using NF-kappaB p105/p50 (Phospho-Ser907) Antibody.
    • Western blot analysis of lysates from HeLa cells treated with TNF-alpha, using NF-kappaB p105/p50 (Phospho-Ser907) Antibody. The lane on the right is blocked with the phospho peptide.