GABA Transporter 1 Polyclonal Antibody
- Catalog No.:YN5590
- Applications:WB;IHC;IF
- Reactivity:Human;Rat;Mouse
- Target:
- GABA T-1
- Fields:
- >>Synaptic vesicle cycle;>>GABAergic synapse
- Gene Name:
- SLC6A1
- Protein Name:
- Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1)
- Human Gene Id:
- 6529
- Human Swiss Prot No:
- P30531
- Mouse Swiss Prot No:
- P31648
- Rat Swiss Prot No:
- P23978
- Immunogen:
- Synthetic Peptide of GABA Transporter 1 AA range: 329-379
- Specificity:
- GABA Transporter 1 protein(A230) detects endogenous levels of GABA Transporter 1
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:1000-2000, IHC 1:100-200. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- SLC6A1;GABATR;GABT1;GAT1;Sodium- and chloride-dependent GABA transporter 1;GAT-1;Solute carrier family 6 member 1
- Observed Band(KD):
- 67kD
- Background:
- The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al., 2009 [PubMed 19077666]).[supplied by OMIM, Jul 2009],
- Function:
- domain:The PDZ domain-binding motif is involved in the interaction with MPP5.,function:Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.,miscellaneous:This protein is the target of psychomotor stimulants such as amphetamines or cocaine.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,subcellular location:Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons.,subunit:Interacts with MPP5.,
- Subcellular Location:
- Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Cell junction, synapse, presynapse . Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons (By similarity). .
- Expression:
- Brain,
- June 19-2018
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- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- September 08-2020
- FLOW-CYTOMEYRT-PROTOCOL
- May 20-2022
- Cell-Based ELISA│解您多样本WB检测之困扰
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- Antibody-FAQs
- Products Images
- Western blot analysis of 1) Mouse Brain Tissue, 2)Rat Brain Tissue with GABA Transporter 1 Rabbit pAb diluted at 1:2,000.
- Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using GABA Transporter 1 Rabbit pAb diluted at 1:200.
- Immunohistochemical analysis of paraffin-embedded Mouse BrainTissue using GABA Transporter 1 Rabbit pAb diluted at 1:200.