L-type Ca++ CP γ5 Polyclonal Antibody
- Catalog No.:YN5520
- Applications:WB;IHC;IF
- Reactivity:Human;Mouse;Rat
- Target:
- L-type Ca++ CP γ5
- Fields:
- >>MAPK signaling pathway;>>Cardiac muscle contraction;>>Adrenergic signaling in cardiomyocytes;>>Oxytocin signaling pathway;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy
- Gene Name:
- CACNG5
- Protein Name:
- Voltage-dependent calcium channel gamma-5 subunit
- Human Gene Id:
- 10369
- Human Swiss Prot No:
- Q9UF02
- Mouse Swiss Prot No:
- Q8VHW4
- Rat Swiss Prot No:
- Q8VHW8
- Immunogen:
- Synthetic Peptide of L-type Ca++ CP γ5 AA range: 110-190
- Specificity:
- The antibody detects endogenous L-type Ca++ CP γ5 protein.
- Formulation:
- PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-1000 IHC 1:100-200. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- CACNG5;Voltage-dependent calcium channel gamma-5 subunit;Neuronal voltage-gated calcium channel gamma-5 subunit;Transmembrane AMPAR regulatory protein gamma-5;TARP gamma-5
- Observed Band(KD):
- 35kD
- Background:
- calcium voltage-gated channel auxiliary subunit gamma 5(CACNG5) Homo sapiens The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. This gene is a susceptibility locus for schizophrenia and bipolar disorder. [provided by RefSeq, Dec 2010],
- Function:
- function:Thought to stabilize the calcium channel in an inactivated (closed) state.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.,
- Subcellular Location:
- Membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic density membrane .
- Expression:
- Brain cortex,Thalamus,
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- Antibody-FAQs
- Products Images
- Western blot analysis of 1) Human Brain Tissue, 2) Mouse Brain Tissue, 3) Rat Brain Tissue using L-type Ca++ CP γ5 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using L-type Ca++ CP γ5 Polyclonal Antibody.