SYEP Polyclonal Antibody

  • Catalog No.:YN2956
  • Applications:WB;ELISA
  • Reactivity:Human;Mouse
    • Target:
    • SYEP
    • Fields:
    • >>Porphyrin metabolism;>>Aminoacyl-tRNA biosynthesis;>>Metabolic pathways;>>Biosynthesis of cofactors
    • Gene Name:
    • EPRS GLNS PARS QARS QPRS PIG32
    • Protein Name:
    • Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) (Cell proliferation-inducing gene 32 protein) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthe
    • Human Gene Id:
    • 2058
    • Human Swiss Prot No:
    • P07814
    • Mouse Swiss Prot No:
    • Q8CGC7
    • Immunogen:
    • Synthesized peptide derived from part region of human protein
    • Specificity:
    • SYEP Polyclonal Antibody detects endogenous levels of protein.
    • Formulation:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:500-2000 ELISA 1:5000-20000
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Observed Band(KD):
    • 166kD
    • Background:
    • Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined. [provided by RefSeq, Jul 2008],
    • Function:
    • catalytic activity:ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).,catalytic activity:ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).,caution:Was originally thought to be a glutaminyl-tRNA synthetase.,domain:The WHEP-TRS domain is involved in RNA binding.,function:Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Sequencing errors.,similarity:Belongs to the class-I aminoacyl-tRNA synthetase family.,similarity:Contains 3 WHEP-TRS domains.,similarity:In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.,similarity:In the N-terminal se
    • Subcellular Location:
    • Cytoplasm, cytosol . Membrane ; Peripheral membrane protein . Translocates from cytosol to membranes upon phosphorylation at Ser-999. .
    • Expression:
    • Bone marrow,Brain,Cervix carcinoma,Duodenum,Epithelium,Eye,Lung,Placenta,