ITB8 Polyclonal Antibody

  • Catalog No.:YN1771
  • Applications:WB,ELISA
  • Reactivity:Human
    • Gene Name:
    • ITGB8
    • Protein Name:
    • Integrin beta-8
    • Human Gene Id:
    • 3696
    • Human Swiss Prot No:
    • P26012
    • Immunogen:
    • Synthesized peptide derived from part region of human protein
    • Specificity:
    • ITB8 Polyclonal Antibody detects endogenous levels of protein.
    • Formulation:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • WB 1:500-2000 ELISA 1:5000-20000
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Observed Band(KD):
    • 84
    • Background:
    • integrin subunit beta 8(ITGB8) Homo sapiens This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008],
    • Function:
    • function:Integrin alpha-V/beta-8 is a receptor for fibronectin.,similarity:Belongs to the integrin beta chain family.,similarity:Contains 1 VWFA domain.,subunit:Heterodimer of an alpha and a beta subunit. Beta-8 associates with alpha-V.,tissue specificity:Placenta, kidney, brain, ovary, uterus and in several transformed cells. Transiently expressed in 293 human embryonic kidney cells.,
    • Subcellular Location:
    • plasma membrane,integrin complex,cell surface,integrin alphav-beta8 complex,extracellular exosome,
    • Expression:
    • Brain,Placenta,Uterus,