ITA10 Polyclonal Antibody

  • Catalog No.:YN1769
  • Applications:WB,ELISA
  • Reactivity:Human
    • Gene Name:
    • ITGA10 UNQ468/PRO827
    • Protein Name:
    • Integrin alpha-10
    • Human Gene Id:
    • 8515
    • Human Swiss Prot No:
    • O75578
    • Immunogen:
    • Synthesized peptide derived from part region of human protein
    • Specificity:
    • ITA10 Polyclonal Antibody detects endogenous levels of protein.
    • Formulation:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • WB 1:500-2000 ELISA 1:5000-20000
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Observed Band(KD):
    • 128
    • Background:
    • integrin subunit alpha 10(ITGA10) Homo sapiens Integrins are integral transmembrane glycoproteins composed of noncovalently linked alpha and beta chains. They participate in cell adhesion as well as cell-surface mediated signalling. This gene encodes an integrin alpha chain and is expressed at high levels in chondrocytes, where it is transcriptionally regulated by AP-2epsilon and Ets-1. The protein encoded by this gene binds to collagen. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
    • Function:
    • domain:The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.,function:Integrin alpha-10/beta-1 is a receptor for collagen.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 1 VWFA domain.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. Alpha-10 associates with beta-1.,tissue specificity:Widely expressed with highest expression in muscle and heart. Found in articular cartilage.,
    • Subcellular Location:
    • plasma membrane,integrin complex,integrin alpha10-beta1 complex,
    • Expression:
    • Articular chondrocyte,Endothelial cell,Heart,