IQGA2 Polyclonal Antibody

  • Catalog No.：YN1154
  • Applications：WB;ELISA
  • Reactivity：Human;Mouse
    • Target：
    • IQGA2
    • Fields：
    • >>Regulation of actin cytoskeleton
    • Gene Name：
    • IQGAP2
    • Protein Name：
    • Ras GTPase-activating-like protein IQGAP2
    • Human Swiss Prot No：
    • Q13576
    • Mouse Swiss Prot No：
    • Q3UQ44
    • Immunogen：
    • Synthesized peptide derived from human protein . at AA range: 200-280
    • Specificity：
    • IQGA2 Polyclonal Antibody detects endogenous levels of protein.
    • Formulation：
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500-2000 ELISA 1:5000-20000
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Observed Band(KD)：
    • 173kD
    • Background：
    • IQ motif containing GTPase activating protein 2(IQGAP2) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. [provided by RefSeq, Jul 2008],
    • Function：
    • function:Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 Ras-GAP domain.,similarity:Contains 1 WW domain.,similarity:Contains 3 IQ domains.,tissue specificity:Isoform 2 expression is enhanced in testis.,
    • Subcellular Location：
    • cytoplasm,cytosol,microtubule,microvillus,cell surface,actin cytoskeleton,lamellipodium,filopodium,filamentous actin,extracellular exosome,
    • Expression：
    • Isoform 2 expression is enhanced in testis.

    Attributes

    • Code：
    • YN1154
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 150 / 280 / 450
    • Delivery：
    • 2024-04-24
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