IQGA2 Polyclonal Antibody

  • Catalog No.:YN1154
  • Applications:WB,ELISA
  • Reactivity:Human,Mouse
    • Gene Name:
    • IQGAP2
    • Protein Name:
    • Ras GTPase-activating-like protein IQGAP2
    • Human Swiss Prot No:
    • Q13576
    • Mouse Swiss Prot No:
    • Q3UQ44
    • Immunogen:
    • Synthesized peptide derived from human protein . at AA range: 200-280
    • Specificity:
    • IQGA2 Polyclonal Antibody detects endogenous levels of protein.
    • Formulation:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • WB 1:500-2000 ELISA 1:5000-20000
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Observed Band(KD):
    • 173
    • Background:
    • IQ motif containing GTPase activating protein 2(IQGAP2) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. [provided by RefSeq, Jul 2008],
    • Function:
    • function:Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 Ras-GAP domain.,similarity:Contains 1 WW domain.,similarity:Contains 3 IQ domains.,tissue specificity:Isoform 2 expression is enhanced in testis.,
    • Subcellular Location:
    • cytoplasm,cytosol,microtubule,microvillus,cell surface,actin cytoskeleton,lamellipodium,filopodium,filamentous actin,extracellular exosome,
    • Expression:
    • Brain,Liver,Platelet,