NGDN Polyclonal Antibody
- Catalog No.:YN0964
- Applications:WB;ELISA
- Reactivity:Human;Mouse
- Target:
- NGDN
- Gene Name:
- NGDN C14orf120
- Protein Name:
- Neuroguidin (EIF4E-binding protein)
- Human Gene Id:
- 25983
- Human Swiss Prot No:
- Q8NEJ9
- Mouse Swiss Prot No:
- Q9DB96
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 240-320
- Specificity:
- NGDN Polyclonal Antibody detects endogenous levels of protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000 ELISA 1:5000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Observed Band(KD):
- 34kD
- Background:
- Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar 2008],
- Function:
- function:Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs.,similarity:Belongs to the SAS10 family.,subcellular location:Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites.,subunit:Interacts with CPEB1 and EIF4E.,
- Subcellular Location:
- Nucleus . Nucleus, nucleolus . Chromosome, centromere . Cytoplasm . Cell projection, axon . Cell projection, dendrite . Cell projection, filopodium . Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites (By similarity). Translocated from nucleolus to nuclear foci in response to UV damage. .
- Expression:
- Brain,Epithelium,Placenta,
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night