NGDN Polyclonal Antibody

    • Catalog No.:YN0964
    • Applications:WB;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • NGDN
      • Gene Name:
      • NGDN C14orf120
      • Protein Name:
      • Neuroguidin (EIF4E-binding protein)
      • Human Swiss Prot No:
      • Q8NEJ9
      • Mouse Swiss Prot No:
      • Q9DB96
      • Immunogen:
      • Synthesized peptide derived from human protein . at AA range: 240-320
      • Specificity:
      • NGDN Polyclonal Antibody detects endogenous levels of protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000 ELISA 1:5000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Observed Band(KD):
      • 34kD
      • Background:
      • Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar 2008],
      • Function:
      • function:Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs.,similarity:Belongs to the SAS10 family.,subcellular location:Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites.,subunit:Interacts with CPEB1 and EIF4E.,
      • Subcellular Location:
      • Nucleus . Nucleus, nucleolus . Chromosome, centromere . Cytoplasm . Cell projection, axon . Cell projection, dendrite . Cell projection, filopodium . Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites (By similarity). Translocated from nucleolus to nuclear foci in response to UV damage. .
      • Expression:
      • Brain,Epithelium,Placenta,
      • Products Images
      • Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night