• Target：
• CCNB2

• Fields：
• >>FoxO signaling pathway;>>Cell cycle;>>Oocyte meiosis;>>p53 signaling pathway;>>Cellular senescence;>>Progesterone-mediated oocyte maturation;>>Human T-cell leukemia virus 1 infection;>>Human immunodeficiency virus 1 infection

• Gene Name：
• CCNB2

• Protein Name：
• G2/mitotic-specific cyclin-B2

• Human Gene Id：
• 9133

• Human Swiss Prot No：
• O95067

• Mouse Swiss Prot No：
• P30276

• Immunogen：
• Synthesized peptide derived from human protein . at AA range: 60-140

• Specificity：
• CCNB2 Polyclonal Antibody detects endogenous levels of protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000 ELISA 1:5000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Observed Band(KD)：
• 43kD

• Background：
• Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. [provided by RefSeq, Jul 2008],

• Function：
• developmental stage:Accumulates steadily during G2 and is abruptly destroyed at mitosis.,function:Essential for the control of the cell cycle at the G2/M (mitosis) transition.,similarity:Belongs to the cyclin family.,similarity:Belongs to the cyclin family. Cyclin AB subfamily.,subunit:Interacts with the CDC2 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.,

• Subcellular Location：
• nucleus,nucleoplasm,centrosome,cytosol,cell-cell adherens junction,microtubule cytoskeleton,membrane,

• Expression：
• Brain,Coronary artery,Testis,

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