Arginase-1(PT1766) mouse mAb

    • Catalog No.:YM6685
    • Applications:IHC-p
    • Reactivity:Human
    • Description
    • Gene Name:
    • ARG1
    • Protein Name:
    • Arginase-1 (EC 3.5.3.1) (Liver-type arginase) (Type I arginase)
    • Human Gene Id:
    • 383
    • Human Swiss Prot No:
    • P05089
    • Immunogen:
    • Synthesized peptide derived from human Arginase-1
    • Specificity:
    • This antibody detects endogenous levels of human Arginase-1 (EC 3.5.3.1) (Liver-type arginase) (Type I arginase)
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Mouse/IgG2a, Kappa
    • Dilution:
    • IHC-p 1:100-500
    • Purification:
    • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Background:
    • Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by ARG1, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.
    • Function:
    • urea cycle, arginine metabolic process, arginine catabolic process, cellular amino acid catabolic process, glutamine family amino acid metabolic process, glutamine family amino acid catabolic process, amine catabolic process, organic acid catabolic process, urea metabolic process, cellular amide metabolic process, amide biosynthetic process, nitrogen compound biosynthetic process, carboxylic acid catabolic process,
    • Products Images
    • Immunohistochemical analysis of paraffin-embedded human Hepatocellular carcinoma. 1,Arginase-1 Antibody was diluted at 1:200(4°,overnight). 2, EDTA pH 8.0 was used for antigen retrieval
    • Immunohistochemical analysis of paraffin-embedded human Hepatocellular carcinoma. 1,Arginase-1 Antibody was diluted at 1:200(4°,overnight). 2, EDTA pH 8.0 was used for antigen retrieval
    • Immunohistochemical analysis of paraffin-embedded human Hepatocellular carcinoma. 1,Arginase-1 Antibody was diluted at 1:200(4°,overnight). 2, EDTA pH 8.0 was used for antigen retrieval
    • Immunohistochemical analysis of paraffin-embedded human Hepatocellular carcinoma. 1,Arginase-1 Antibody was diluted at 1:200(4°,overnight). 2, EDTA pH 8.0 was used for antigen retrieval