CD80 Monoclonal Antibody

    • Catalog No.:YM0136
    • Applications:IHC;IF;ELISA
    • Reactivity:Human
      • Target:
      • CD80
      • Fields:
      • >>Cell adhesion molecules;>>Toll-like receptor signaling pathway;>>Intestinal immune network for IgA production;>>Type I diabetes mellitus;>>Autoimmune thyroid disease;>>Systemic lupus erythematosus;>>Rheumatoid arthritis;>>Allograft rejection;>>Graft-versus-host disease;>>Viral myocarditis
      • Gene Name:
      • CD80
      • Protein Name:
      • T-lymphocyte activation antigen CD80
      • Human Gene Id:
      • 941
      • Human Swiss Prot No:
      • P33681
      • Mouse Swiss Prot No:
      • Q00609
      • Immunogen:
      • Purified recombinant fragment of CD80 expressed in E. Coli.
      • Specificity:
      • CD80 Monoclonal Antibody detects endogenous levels of CD80 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Monoclonal, Mouse
      • Dilution:
      • IHC 1:200 - 1:1000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
      • Purification:
      • Affinity purification
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • CD80;CD28LG;CD28LG1;LAB7;T-lymphocyte activation antigen CD80;Activation B7-1 antigen;BB1;CTLA-4 counter-receptor B7.1;B7;CD antigen CD80
      • References:
      • 1. Transplant Proc. 2008 Oct;40(8):2729-33.
        2. Nat Med. 2007 Dec;13(12):1440-9.
      • Background:
      • The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011],
      • Function:
      • function:Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.,tissue specificity:Expressed on activated B-cells, macrophages and dendritic cells.,
      • Subcellular Location:
      • Membrane; Single-pass type I membrane protein.
      • Expression:
      • Expressed on activated B-cells, macrophages and dendritic cells.
      • Products Images
      • Immunohistochemistry analysis of paraffin-embedded human Tonsil tissues with AEC staining using CD80 Monoclonal Antibody.
      • Confocal immunofluorescence analysis of BCBL-1 cells using CD80 Monoclonal Antibody (green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.