Total Cox-2 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3232C
  • Applications:ELISA
  • Reactivity:Human
    • Gene Name:
    • PTGS2
    • Human Gene Id:
    • 5743
    • Human Swiss Prot No:
    • P35354
    • Mouse Swiss Prot No:
    • Q05769
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2)
    • Detection Method:
    • Colorimetric
    • Background:
    • catalytic activity:Arachidonate + AH(2) + 2 O(2) = prostaglandin H(2) + A + H(2)O.,cofactor:Binds 1 heme B (iron-protoporphyrin IX) group per subunit.,disease:Likely to play a role in inflammatory diseases such as rheumatoid arthritis.,function:May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.,induction:By cytokines and mitogens.,miscellaneous:This enzyme acts both as a dioxygenase and as a peroxidase.,miscellaneous:This enzyme is the target of nonsteroidal anti-inflammatory drugs such as aspirin.,pathway:Lipid metabolism; prostaglandin biosynthesis.,similarity:Belongs to the prostaglandin G/H synthase family.,similarity:Contains 1 EGF-like domain.,subunit:Homodimer.,
    • Function:
    • very-long-chain fatty acid metabolic process, skeletal system development, ossification, prostaglandin biosynthetic process, placenta development, maternal placenta development, hair follicle development, response to molecule of bacterial origin, reproductive developmental process, circulatory system process, fatty acid metabolic process, fatty acid biosynthetic process, unsaturated fatty acid biosynthetic process, icosanoid metabolic process, prostanoid metabolic process, prostaglandin metabolic process, cell motion, regulation of muscle contraction, regulation of smooth muscle contraction, response to oxidative stress, gamete generation, female gamete generation, ectoderm development, female pregnancy, embryo implantation, response to nutrient, behavior, learning or memory, memory,blood circulation, regulation of blood pressure, positive regulation of cell proliferation, negative regul
    • Subcellular Location:
    • Microsome membrane ; Peripheral membrane protein. Endoplasmic reticulum membrane ; Peripheral membrane protein. Nucleus inner membrane ; Peripheral membrane protein. Nucleus outer membrane ; Peripheral membrane protein. Detected on the lumenal side of the endoplasmic reticulum and nuclear envelope. .