IL-34 rabbit pAb

  • 货号:YT7847
  • 应用:WB;ELISA
  • 种属:Human;Rat;Mouse;
    • 靶点:
    • IL-34
    • 简介:
    • >>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor
    • 基因名称:
    • IL34 C16orf77
    • 蛋白名称:
    • IL-34
    • Human Swiss Prot No:
    • Q6ZMJ4
    • Mouse Swiss Prot No:
    • Q8R1R4
    • 免疫原:
    • Synthesized peptide derived from human IL-34 AA range: 51-100
    • 特异性:
    • This antibody detects endogenous levels of Human IL-34
    • 组成:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • 来源:
    • Polyclonal, Rabbit,IgG
    • 稀释:
    • WB 1:1000-2000 ELISA 1:5000-20000
    • 纯化工艺:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 其他名称:
    • Interleukin-34 (IL-34)
    • 分子量:
    • 27kD
    • 背景:
    • Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008],
    • 功能:
    • function:Cytokine that promotes the differentiation and viability of monocytes and macrophages. Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Ligand for colony-stimulating factor-1 receptor CSF1R.,similarity:Belongs to the IL-34 family.,subunit:Homodimer.,tissue specificity:Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.,
    • 细胞定位:
    • Secreted .
    • 组织表达:
    • Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.