IL-8RA Polyclonal Antibody

    • 货号:YT6039
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human
      • 靶点:
      • IL-8RA
      • 简介:
      • >>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway;>>Phospholipase D signaling pathway;>>Endocytosis;>>Epithelial cell signaling in Helicobacter pylori infection
      • 基因名称:
      • CXCR1 CMKAR1 IL8RA
      • 蛋白名称:
      • C-X-C chemokine receptor type 1 (CXC-R1) (CXCR-1) (CDw128a) (High affinity interleukin-8 receptor A) (IL-8R A) (IL-8 receptor type 1) (CD antigen CD181)
      • Human Gene Id:
      • 3577
      • Human Swiss Prot No:
      • P25024
      • Mouse Swiss Prot No:
      • Q810W6
      • 免疫原:
      • Synthetic peptide from human protein at AA range: 1-50
      • 特异性:
      • The antibody detects endogenous IL-8RA
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000 IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • C-X-C chemokine receptor type 1 (CXC-R1;CXCR-1;CDw128a;High affinity interleukin-8 receptor A;IL-8R A;IL-8 receptor type 1;CD antigen CD181)
      • 分子量:
      • 40kD
      • 背景:
      • C-X-C motif chemokine receptor 1(CXCR1) Homo sapiens The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008],
      • 功能:
      • function:Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.,online information:CXC chemokine receptors entry,similarity:Belongs to the G-protein coupled receptor 1 family.,
      • 细胞定位:
      • Cell membrane; Multi-pass membrane protein.
      • 组织表达:
      • Blood,Placenta,

      CSF2 upregulates CXCL3 expression in adipocytes to promote metastasis of breast cancer via the FAK signaling pathway Journal of Molecular Cell Biology Xiangyang Xiong WB Human MCF10A cell,MDA-MB-231 cell,BT549 cell,MCF-7 cell,T47D cell
      货号:YT6039

      • 产品图片
      • Immunohistochemical analysis of paraffin-embedded Human-liver-cancer, antibody was diluted at 1:100
      • Immunohistochemical analysis of paraffin-embedded Human-placenta, antibody was diluted at 1:100