• 靶点：
• C7

• 简介：
• >>Complement and coagulation cascades;>>Prion disease;>>Coronavirus disease - COVID-19;>>Systemic lupus erythematosus

• 基因名称：
• C7

• 蛋白名称：
• Complement component C7

• Human Gene Id：
• 730

• Human Swiss Prot No：
• P10643

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the N-terminal region of human C7. AA range:100-150

• 特异性：
• C7 Polyclonal Antibody detects endogenous levels of C7 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• C7;Complement component C7

• 实测条带：
• 93kD

• 背景：
• C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. [provided by RefSeq, Jul 2008],

• 功能：
• disease:Defects in C7 are a cause of component C7 deficiency (C7D) [MIM:217070]. Patients with C7D suffer from recurrent bacterial infections, predominantly from Neisseria meningitidis.,function:C7 is a constituent of the membrane attack complex. C7 binds to C5b forming the C5b-7 complex, where it serves as a membrane anchor.,online information:C7 mutation db,PTM:C7 has 28 disulfide bridges.,similarity:Belongs to the complement C6/C7/C8/C9 family.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 LDL-receptor class A domain.,similarity:Contains 1 MACPF domain.,similarity:Contains 2 Sushi (CCP/SCR) domains.,similarity:Contains 2 TSP type-1 domains.,subunit:Monomer or dimer; as a C5b-7 complex it can also form multimeric rosettes.,

• 细胞定位：
• Secreted.

• 组织表达：
• Liver,Placenta,Plasma,PNS,

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