SCYL1BP1 Polyclonal Antibody
- 货号:YT5369
- 应用:WB;ELISA;IHC
- 种属:Human;Mouse;Rat
- 简介:
- >>p53 signaling pathway
- 蛋白名称:
- RAB6-interacting golgin
- 免疫原:
- The antiserum was produced against synthesized peptide derived from the N-terminal region of human GORAB. AA range:1-50
- 特异性:
- SCYL1BP1 Polyclonal Antibody detects endogenous levels of SCYL1BP1 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- GORAB;NTKLBP1;SCYL1BP1;RAB6-interacting golgin;N-terminal kinase-like-binding protein 1;NTKL-BP1;NTKL-binding protein 1;hNTKL-BP1;SCY1-like 1-binding protein 1;SCYL1-BP1;SCYL1-binding protein 1
- 背景:
- golgin, RAB6 interacting(GORAB) Homo sapiens This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been associated with geroderma osteodysplastica. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009],
- 功能:
- caution:It is uncertain whether Met-1 or Met-26 is the initiator.,disease:Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.,similarity:Belongs to the GORAB family.,subunit:Interacts with SCYL1 (By similarity). Interacts with RCHY1 and RAB6A/RAB6.,
- 细胞定位:
- Cytoplasm . Golgi apparatus .
- 组织表达:
- Embryo,Pancreas,Testis,Trachea,
- Western Blot analysis of AD293 cells using SCYL1BP1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Western blot analysis of lysate from AD293 cells, using GORAB Antibody.
- Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).