• 靶点：
• ZHX2

• 基因名称：
• ZHX2

• 蛋白名称：
• Zinc fingers and homeoboxes protein 2

• Human Gene Id：
• 22882

• Human Swiss Prot No：
• Q9Y6X8

• Mouse Gene Id：
• 387609

• Mouse Swiss Prot No：
• Q8C0C0

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human ZHX2. AA range:751-800

• 特异性：
• ZHX2 Polyclonal Antibody detects endogenous levels of ZHX2 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• ZHX2;AFR1;KIAA0854;RAF;Zinc fingers and homeoboxes protein 2;Alpha-fetoprotein regulator 1;AFP regulator 1;Regulator of AFP;Zinc finger and homeodomain protein 2

• 实测条带：
• 92kD

• 背景：
• The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008],

• 功能：
• function:Acts as a transcriptional repressor.,similarity:Belongs to the ZHX family.,similarity:Contains 2 C2H2-type zinc fingers.,similarity:Contains 4 homeobox DNA-binding domains.,subunit:Forms homodimers. Also forms heterodimers with ZHX1 and ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts with NFYA.,tissue specificity:Ubiquitously expressed.,

• 细胞定位：
• Nucleus . Colocalizes with EFNB1 intracellular domain in the nucleus. .

• 组织表达：
• Ubiquitously expressed. Expressed in podocytes.

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