• 靶点：
• VHX

• 基因名称：
• DUSP22

• 蛋白名称：
• Dual specificity protein phosphatase 22

• Human Gene Id：
• 56940

• Human Swiss Prot No：
• Q9NRW4

• Mouse Gene Id：
• 105352

• Mouse Swiss Prot No：
• Q99N11

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human DUSP22. AA range:121-170

• 特异性：
• VHX Polyclonal Antibody detects endogenous levels of VHX protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• DUSP22;JSP1;LMWDSP2;MKPX;Dual specificity protein phosphatase 22;JNK-stimulatory phosphatase-1;JSP-1;Low molecular weight dual specificity phosphatase 2;LMW-DSP2;Mitogen-activated protein kinase phosphatase x;MAP kinase phosphatas

• 实测条带：
• 21kD

• 背景：
• catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK).,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,tissue specificity:Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.,

• 功能：
• catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK).,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,tissue specificity:Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.,

• 细胞定位：
• Cytoplasm .

• 组织表达：
• Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.

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