Tip5 Polyclonal Antibody

    • 货号:YT4663
    • 应用:WB,ELISA
    • 种属:Human
      • 基因名称:
      • BAZ2A
      • 蛋白名称:
      • Bromodomain adjacent to zinc finger domain protein 2A
      • Human Swiss Prot No:
      • Q9UIF9
      • Mouse Swiss Prot No:
      • Q91YE5
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human BAZ2A. AA range:1281-1330
      • 特异性:
      • Tip5 Polyclonal Antibody detects endogenous levels of Tip5 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Rabbit
      • 稀释:
      • Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -20°C/1 year
      • 其他名称:
      • BAZ2A; KIAA0314; TIP5; Bromodomain adjacent to zinc finger domain protein 2A; Transcription termination factor I-interacting protein 5; TTF-I-interacting protein 5; Tip5; hWALp3
      • 分子量:
      • 208361
      • 实测条带:
      • 210
      • 背景:
      • function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the WAL family.,similarity:Contains 1 bromo domain.,similarity:Contains 1 DDT domain.,similarity:Contains 1 MBD (methyl-CpG-binding) domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 4 A.T hook DNA-binding domains.,subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus.,subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex).,tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.,
      • 功能:
      • function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the WAL family.,similarity:Contains 1 bromo domain.,similarity:Contains 1 DDT domain.,similarity:Contains 1 MBD (methyl-CpG-binding) domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 4 A.T hook DNA-binding domains.,subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus.,subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex).,tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney
      • 细胞定位:
      • nucleus,nucleoplasm,chromatin silencing complex,nucleolus,cytoplasm,rDNA heterochromatin,
      • 组织表达:
      • Brain,Epithelium,Lung,Lymph,Testis,
      • 产品图片
      • Western blot analysis of the lysates from HeLa cells using BAZ2A antibody.