StARD13 Polyclonal Antibody

    • 货号:YT4438
    • 应用:WB;ELISA;IHC
    • 种属:Human;Mouse
      • 靶点:
      • StARD13
      • 基因名称:
      • STARD13
      • 蛋白名称:
      • StAR-related lipid transfer protein 13
      • Human Swiss Prot No:
      • Q9Y3M8
      • Mouse Swiss Prot No:
      • Q923Q2
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human STA13. AA range:101-150
      • 特异性:
      • StARD13 Polyclonal Antibody detects endogenous levels of StARD13 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • STARD13;DLC2;GT650;StAR-related lipid transfer protein 13;46H23.2;Deleted in liver cancer 2 protein;DLC-2;Rho GTPase-activating protein;START domain-containing protein 13;StARD13
      • 实测条带:
      • 125kD
      • 背景:
      • This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011],
      • 功能:
      • function:GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 1 START domain.,subunit:Homodimer. Interacts with TAX1BP1.,tissue specificity:Ubiquitously expressed. Underexpressed in hepatocellular carcinoma cells and some breast cancer cell lines.,
      • 细胞定位:
      • Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion membrane; Peripheral membrane protein; Cytoplasmic side. Lipid droplet.
      • 组织表达:
      • Ubiquitously expressed. Underexpressed in hepatocellular carcinoma cells and some breast cancer cell lines.
      • 产品图片
      • Western blot analysis of STA13 Antibody. The lane on the right is blocked with the STA13 peptide.
      • Immunofluorescence analysis of A549 cells, using STA13 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).