Rab 24 Polyclonal Antibody
- 货号：YT3923
- 应用：IHC;IF;ELISA
- 种属：Human;Mouse;Rat
- 蛋白名称：
- Ras-related protein Rab-24
- 免疫原：
- Synthesized peptide derived from Rab 24 . at AA range: 90-170
- 特异性：
- Rab 24 Polyclonal Antibody detects endogenous levels of Rab 24 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- RAB24;Ras-related protein Rab-24
- 背景：
- RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein trafficking (Olkkonen et al., 1993 [PubMed 8126105]).[supplied by OMIM, Aug 2009],
- 功能：
- function:May be involved in autophagy-related processes.,induction:By extensive retinoic acid treatment, in Ntera-2 teratoma cell line induced to differentiate into post-mitotic neurons (NTN2) (at protein level).,miscellaneous:The unusual Ser-67, instead of a conserved Gln in other family members, is the cause of low GTPase activity. As a result, the predominant nucleotide associated with the protein is GTP.,PTM:Isoprenylation is inefficient compared to other Rab family members.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Only about 20-25% is recovered in the particulate fraction.,subunit:Unlike other Rab family members, does not interact with GDP dissociation inhibitors (GDIs), including ARHGDIA and ARHGDIB.,
- 细胞定位：
- Cytoplasm, cytosol . Membrane ; Lipid-anchor . Only about 20-25% is recovered in the particulate fraction. .
- 组织表达：
- Amygdala,Pancreas,Skin,Uterus,Whole embryo,
- Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
