• 靶点：
• Nkx-6.1

• 简介：
• >>Maturity onset diabetes of the young

• 基因名称：
• NKX6-1

• 蛋白名称：
• Homeobox protein Nkx-6.1

• Human Gene Id：
• 4825

• Human Swiss Prot No：
• P78426

• Mouse Gene Id：
• 18096

• Mouse Swiss Prot No：
• Q99MA9

• Rat Gene Id：
• 65193

• Rat Swiss Prot No：
• O35762

• 免疫原：
• Synthesized peptide derived from Nkx-6.1 . at AA range: 180-260

• 特异性：
• Nkx-6.1 Polyclonal Antibody detects endogenous levels of Nkx-6.1 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• NKX6-1;NKX6A;Homeobox protein Nkx-6.1;Homeobox protein NK-6 homolog A

• 分子量：
• 38kD

• 背景：
• In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008],

• 功能：
• function:May be important for control of islet development and/or regulation of insulin biosynthesis.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Pancreatic beta cells.,

• 细胞定位：
• Nucleus .

• 组织表达：
• Pancreatic beta cells.

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