NCKX6 Polyclonal Antibody

    • 货号:YT2995
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • NCKX6
      • 基因名称:
      • SLC24A6
      • 蛋白名称:
      • Sodium/potassium/calcium exchanger 6
      • Human Swiss Prot No:
      • Q6J4K2
      • Mouse Swiss Prot No:
      • Q925Q3
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human SLC24A6. AA range:494-543
      • 特异性:
      • NCKX6 Polyclonal Antibody detects endogenous levels of NCKX6 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • SLC24A6;NCKX6;NCLX;Sodium/potassium/calcium exchanger 6;Na(+)/K(+)/Ca(2+)-exchange protein 6;Solute carrier family 24 member 6
      • 实测条带:
      • 60kD
      • 背景:
      • SLC24A6 belongs to a family of potassium-dependent sodium/calcium exchangers that maintain cellular calcium homeostasis through the electrogenic countertransport of 4 sodium ions for 1 calcium ion and 1 potassium ion (Cai and Lytton, 2004 [PubMed 14625281]).[supplied by OMIM, Mar 2008],
      • 功能:
      • function:Transports Ca(2+) in exchange for either Li(+) or Na(+), explaining how Li(+) catalyzes Ca(2+) exchange. In contrast to other members of the family its function is independent of K(+).,miscellaneous:Strongly inhibited by zinc.,similarity:Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.,
      • 细胞定位:
      • Mitochondrion inner membrane ; Multi-pass membrane protein .
      • 组织表达:
      • Present in pancreatic beta-cells (at protein level).
      • 产品图片
      • Western blot analysis of lysates from MCF-7 cells, using SLC24A6 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from HeLa cells using SLC24A6 antibody.
      • Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).