CMTM4 Polyclonal Antibody

    • 货号:YT0986
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human;Mouse
      • 靶点:
      • CMTM4
      • 基因名称:
      • CMTM4
      • 蛋白名称:
      • CKLF-like MARVEL transmembrane domain-containing protein 4
      • Human Swiss Prot No:
      • Q8IZR5
      • Mouse Swiss Prot No:
      • Q8CJ61
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human CKLF4. AA range:161-210
      • 特异性:
      • CMTM4 Polyclonal Antibody detects endogenous levels of CMTM4 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • CMTM4;CKLFSF4;CKLF-like MARVEL transmembrane domain-containing protein 4;Chemokine-like factor superfamily member 4
      • 实测条带:
      • 26kD
      • 背景:
      • This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
      • 功能:
      • similarity:Belongs to the chemokine-like factor family.,similarity:Contains 1 MARVEL domain.,tissue specificity:Highly expressed in testis and prostate.,
      • 细胞定位:
      • Membrane ; Multi-pass membrane protein .
      • 组织表达:
      • Highly expressed in testis and prostate.

      CMTM4 regulates epithelial–mesenchymal transition and PD-L1 expression in head and neck squamous cell carcinoma. MOLECULAR CARCINOGENESIS Mol Carcinogen. 2021 Aug;60(8):556-566 IHC Human mucosa,dysplasia tissue,HNSCC tissue
      货号:YT0986

      • 产品图片
      • Immunofluorescence analysis of A549. 1,primary Antibody(red) was diluted at 1:200(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 594 Secondary antibody was diluted at 1:1000(room temperature, 50min).3, Picture B: DAPI(blue) 10min.
      • Western Blot analysis of HELA cells using CMTM4 Polyclonal Antibody
      • Western blot analysis of CKLF4 Antibody. The lane on the right is blocked with the CKLF4 peptide.
      • Immunohistochemistryt analysis of paraffin-embedded human breast carcinoma, using CKLF4 Antibody. The lane on the right is blocked with the CKLF4 peptide.