ARHGAP11A Polyclonal Antibody
- 货号：YT0314
- 应用：WB;ELISA
- 种属：Human;Rat;Mouse;
- 蛋白名称：
- Rho GTPase-activating protein 11A
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human ARHGAP11A. AA range:471-520
- 特异性：
- ARHGAP11A Polyclonal Antibody detects endogenous levels of ARHGAP11A protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- ARHGAP11A;KIAA0013;Rho GTPase-activating protein 11A;Rho-type GTPase-activating protein 11A
- 背景：
- This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line. [provided by RefSeq, Sep 2016],
- 功能：
- similarity:Contains 1 Rho-GAP domain.,
- 组织表达：
- Bone marrow,Epithelium,Eye,Testis,Uterus,
- Western blot analysis of ARHGAP11A Antibody. The lane on the right is blocked with the ARHGAP11A peptide.
