• 靶点：
• ARF4

• 简介：
• >>Endocytosis

• 基因名称：
• ARF4

• 蛋白名称：
• ADP-ribosylation factor 4

• Human Gene Id：
• 378

• Human Swiss Prot No：
• P18085

• Mouse Swiss Prot No：
• P61750

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human ARF4. AA range:71-120

• 特异性：
• ARF4 Polyclonal Antibody detects endogenous levels of ARF4 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• ARF4;ARF2;ADP-ribosylation factor 4

• 实测条带：
• 25kD

• 背景：
• ADP ribosylation factor 4(ARF4) Homo sapiens This gene is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 5 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. The ARF proteins are categorized as class I, class II and class III; this gene is a class II member. The members of each class share a common gene organization. The ARF4 gene spans approximately 12kb and contains six exons and five introns. This gene is the most divergent member of the human ARFs. Conflicting map positions at 3p14 or 3p21 have been reported for this gene. [provided by RefSeq, Jul 2008],

• 功能：
• caution:Was originally thought to be ARF2.,function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.,similarity:Belongs to the small GTPase superfamily. Arf family.,

• 细胞定位：
• Golgi apparatus. Membrane ; Lipid-anchor .

• 组织表达：
• Bone marrow,Brain,Cerebellum,Placenta,Skin,Urinary bladder,

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