ALS Polyclonal Antibody

    • 货号:YT0201
    • 应用:WB;ELISA
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • ALS
      • 简介:
      • >>Growth hormone synthesis, secretion and action
      • 基因名称:
      • IGFALS
      • 蛋白名称:
      • Insulin-like growth factor-binding protein complex acid labile subunit
      • Human Gene Id:
      • 3483
      • Human Swiss Prot No:
      • P35858
      • Mouse Swiss Prot No:
      • P70389
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human IGFALS. AA range:303-352
      • 特异性:
      • ALS Polyclonal Antibody detects endogenous levels of ALS protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • IGFALS;ALS;Insulin-like growth factor-binding protein complex acid labile subunit;ALS
      • 实测条带:
      • 66kD
      • 背景:
      • The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],
      • 功能:
      • function:Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.,similarity:Contains 20 LRR (leucine-rich) repeats.,subunit:Forms a ternary complex of about 140 to 150 kDa with IGF-I or IGF-II and IGFBP-3.,tissue specificity:Plasma.,
      • 细胞定位:
      • Secreted, extracellular space.
      • 组织表达:
      • Plasma.
      • 产品图片
      • Western Blot analysis of CoLo cells using ALS Polyclonal Antibody
      • Western blot analysis of IGFALS Antibody. The lane on the right is blocked with the IGFALS peptide.
      • Western blot analysis of the lysates from RAW264.7cells using IGFALS antibody.