Adenosine A1-R Polyclonal Antibody
- 货号：YT0128
- 应用：WB;IF;ELISA
- 种属：Human;Rat
- 简介：
- >>cGMP-PKG signaling pathway;>>cAMP signaling pathway;>>Sphingolipid signaling pathway;>>Neuroactive ligand-receptor interaction;>>Regulation of lipolysis in adipocytes;>>Renin secretion;>>Morphine addiction
- 蛋白名称：
- Adenosine receptor A1
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human ADORA1. AA range:277-326
- 特异性：
- Adenosine A1-R Polyclonal Antibody detects endogenous levels of Adenosine A1-R protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- ADORA1;Adenosine receptor A1
- 背景：
- The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008],
- 功能：
- function:Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.,
- 细胞定位：
- Cell membrane ; Multi-pass membrane protein.
- 组织表达：
- Brain,Heart,Hippocampus,
- Western blot analysis of lysates from MCF-7 cells, using ADORA1 Antibody. The lane on the right is blocked with the synthesized peptide.
