• 靶点：
• DKK4

• 简介：
• >>Wnt signaling pathway;>>Alzheimer disease;>>Pathways of neurodegeneration - multiple diseases

• 基因名称：
• DKK4

• 蛋白名称：
• Dickkopf-related protein 4 (Dickkopf-4) (Dkk-4) (hDkk-4) [Cleaved into: Dickkopf-related protein 4 short form]

• Human Gene Id：
• 27121

• Human Swiss Prot No：
• Q9UBT3

• Mouse Swiss Prot No：
• Q8VEJ3

• 免疫原：
• Synthesized peptide derived from human protein . at AA range: 150-230

• 特异性：
• DKK4 Polyclonal Antibody detects endogenous levels of protein.

• 组成：
• Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000 ELISA 1:5000-20000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 实测条带：
• 24kD

• 背景：
• This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. Activity of this protein is modulated by binding to the Wnt co-receptor and the co-factor kremen 2. [provided by RefSeq, Jul 2008],

• 功能：
• function:Inhibitor of Wnt signaling pathway.,PTM:Appears to be not glycosylated.,PTM:Can be proteolytically processed by a furin-like protease.,similarity:Belongs to the dickkopf family.,tissue specificity:Expressed in cerebellum, T-cells, esophagus and lung.,

• 细胞定位：
• Secreted.

• 组织表达：
• Expressed in cerebellum, T-cells, esophagus and lung.

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