ITB8 Polyclonal Antibody

  • 货号:YN1771
  • 应用:WB;ELISA
  • 种属:Human;Rat;Mouse;
    • 靶点:
    • ITB8
    • 简介:
    • >>PI3K-Akt signaling pathway;>>Focal adhesion;>>ECM-receptor interaction;>>Cell adhesion molecules;>>Regulation of actin cytoskeleton;>>Human papillomavirus infection;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy
    • 基因名称:
    • ITGB8
    • 蛋白名称:
    • Integrin beta-8
    • Human Gene Id:
    • 3696
    • Human Swiss Prot No:
    • P26012
    • 免疫原:
    • Synthesized peptide derived from part region of human protein
    • 特异性:
    • ITB8 Polyclonal Antibody detects endogenous levels of protein.
    • 组成:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • 来源:
    • Polyclonal, Rabbit,IgG
    • 稀释:
    • WB 1:500-2000 ELISA 1:5000-20000
    • 纯化工艺:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 实测条带:
    • 84kD
    • 背景:
    • This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008],
    • 功能:
    • function:Integrin alpha-V/beta-8 is a receptor for fibronectin.,similarity:Belongs to the integrin beta chain family.,similarity:Contains 1 VWFA domain.,subunit:Heterodimer of an alpha and a beta subunit. Beta-8 associates with alpha-V.,tissue specificity:Placenta, kidney, brain, ovary, uterus and in several transformed cells. Transiently expressed in 293 human embryonic kidney cells.,
    • 细胞定位:
    • Cell membrane ; Single-pass type I membrane protein .
    • 组织表达:
    • Placenta, kidney, brain, ovary, uterus and in several transformed cells. Transiently expressed in 293 human embryonic kidney cells.