ITA10 Polyclonal Antibody

  • 货号:YN1769
  • 应用:WB;ELISA
  • 种属:Human;Rat;Mouse;
    • 靶点:
    • ITA10
    • 简介:
    • >>PI3K-Akt signaling pathway;>>Focal adhesion;>>ECM-receptor interaction;>>Regulation of actin cytoskeleton;>>Human papillomavirus infection;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy
    • 基因名称:
    • ITGA10 UNQ468/PRO827
    • 蛋白名称:
    • Integrin alpha-10
    • Human Gene Id:
    • 8515
    • Human Swiss Prot No:
    • O75578
    • 免疫原:
    • Synthesized peptide derived from part region of human protein
    • 特异性:
    • ITA10 Polyclonal Antibody detects endogenous levels of protein.
    • 组成:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • 来源:
    • Polyclonal, Rabbit,IgG
    • 稀释:
    • WB 1:500-2000 ELISA 1:5000-20000
    • 纯化工艺:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 实测条带:
    • 128kD
    • 背景:
    • Integrins are integral transmembrane glycoproteins composed of noncovalently linked alpha and beta chains. They participate in cell adhesion as well as cell-surface mediated signalling. This gene encodes an integrin alpha chain and is expressed at high levels in chondrocytes, where it is transcriptionally regulated by AP-2epsilon and Ets-1. The protein encoded by this gene binds to collagen. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
    • 功能:
    • domain:The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.,function:Integrin alpha-10/beta-1 is a receptor for collagen.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 1 VWFA domain.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. Alpha-10 associates with beta-1.,tissue specificity:Widely expressed with highest expression in muscle and heart. Found in articular cartilage.,
    • 细胞定位:
    • Membrane; Single-pass type I membrane protein.
    • 组织表达:
    • Widely expressed with highest expression in muscle and heart. Found in articular cartilage.