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WB 试剂
- PonceauS Staining Solution
- PBST Washing Buffer, 10X
- 1.5M Tris-HCl Buffer, pH8.8
- 1M Tris-HCl Buffer, pH6.8
- 10% SDS Solution
- Prestained Protein Marker
- TBST Washing Buffer, 10X
- SDS PAGE Loading Buffer, 5X
- Stripping Buffered Solution
- Tris Buffer, pH7.4, 10X
- Total Protein Extraction Kit
- Running Buffer, 10X
- Transfer Buffer, 10X
- 30% Acr-Bis(29:1) Solution
- Tris电泳液速溶颗粒
- PBS(1X, premixed powder)
- TBS(1X, premixed powder)
- 快速封闭液
- 转膜液速溶颗粒
- Chemical reagents
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RAC3 Polyclonal Antibody
- 货号:YN1163
- 应用:WB;ELISA
- 种属:Human;Mouse
- 简介:
- >>MAPK signaling pathway;>>Ras signaling pathway;>>Rap1 signaling pathway;>>cAMP signaling pathway;>>Chemokine signaling pathway;>>Sphingolipid signaling pathway;>>Wnt signaling pathway;>>Axon guidance;>>VEGF signaling pathway;>>Focal adhesion;>>Adherens junction;>>Natural killer cell mediated cytotoxicity;>>B cell receptor signaling pathway;>>Fc epsilon RI signaling pathway;>>Regulation of actin cytoskeleton;>>Yersinia infection;>>Human cytomegalovirus infection;>>Human immunodeficiency virus 1 infection;>>Pathways in cancer;>>Colorectal cancer;>>Pancreatic cancer;>>Choline metabolism in cancer;>>Viral myocarditis;>>Fluid shear stress and atherosclerosis
- 蛋白名称:
- Ras-related C3 botulinum toxin substrate 3 (p21-Rac3)
- 免疫原:
- Synthesized peptide derived from human protein . at AA range: 80-160
- 特异性:
- RAC3 Polyclonal Antibody detects endogenous levels of protein.
- 组成:
- Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000 ELISA 1:5000-20000
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 背景:
- The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
- 功能:
- function:Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles.,induction:Expression down-regulated in quiescent fibroblasts and clearly induced by serum stimulation.,similarity:Belongs to the small GTPase superfamily. Rho family.,subcellular location:Membrane-associated when activated. Co-localizes with NRBP to endomembranes and at the cell periphery in lamellipodia.,subunit:Interacts with the GEF protein DOCK7, which promotes the exchange between GDP and GTP, and therefore activates it. Interacts with C1D.,tissue specificity:Highest levels in brain, also detected in heart, placenta and pancreas.,
- 细胞定位:
- Cytoplasm. Endomembrane system. Cell projection, lamellipodium. Cytoplasm, perinuclear region. Cell membrane. Cytoplasm, cytoskeleton. Membrane-associated when activated. Colocalizes with NRBP to endomembranes and at the cell periphery in lamellipodia. Colocalized with CIB1 in the perinuclear area and at the cell periphery.
- 组织表达:
- Highest levels in brain, also detected in heart, placenta and pancreas.
- Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night