Tyro3 Monoclonal Antibody

    • 货号:YM0639
    • 应用:WB;IF;ELISA
    • 种属:Human
      • 靶点:
      • Tyro3
      • 基因名称:
      • TYRO3
      • 蛋白名称:
      • Tyrosine-protein kinase receptor TYRO3
      • Human Gene Id:
      • 7301
      • Human Swiss Prot No:
      • Q06418
      • Mouse Swiss Prot No:
      • P55144
      • 免疫原:
      • Purified recombinant fragment of Tyro3 expressed in E. Coli.
      • 特异性:
      • Tyro3 Monoclonal Antibody detects endogenous levels of Tyro3 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Monoclonal, Mouse
      • 稀释:
      • WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
      • 纯化工艺:
      • Affinity purification
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • TYRO3;BYK;DTK;RSE;SKY;Tyrosine-protein kinase receptor TYRO3;Tyrosine-protein kinase DTK;Tyrosine-protein kinase RSE;Tyrosine-protein kinase SKY;Tyrosine-protein kinase byk
      • 背景:
      • The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010],
      • 功能:
      • catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:May be involved in cell adhesion processes, particularly in the central nervous system. In case of filovirus infection, seems to function as a cell entry factor.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Monomer and homodimer. Interacts with GAS6.,tissue specificity:Abundant in the brain and lower levels in other tissues.,
      • 细胞定位:
      • Cell membrane; Single-pass type I membrane protein.
      • 组织表达:
      • Abundant in the brain and lower levels in other tissues.
      • 产品图片
      • Western Blot analysis using Tyro3 Monoclonal Antibody against truncated Tyro3 recombinant protein.
      • Immunofluorescence staining of methanol-fixed MCF-7 and HepG2 cells showing membrane and cytoplasmic localization using Tyro3 Monoclonal Antibody.