• 基因名称：
• XRCC3

• Human Gene Id：
• 7517

• Human Swiss Prot No：
• O43542

• Mouse Swiss Prot No：
• Q9CXE6

• 储存：
• 2-8°C/6 months

• 其他名称：
• DNA repair protein XRCC3 (X-ray repair cross-complementing protein 3)

• 检测方法：
• Colorimetric

• 背景：
• disease:Met-241 is associated with the development of cutaneous malignant melanoma.,function:Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the recA family. RAD51 subfamily.,subunit:Interacts with RAD51C and RAD51. Part of a complex consisting of RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3.,

• 功能：
• DNA metabolic process, DNA repair, DNA recombination, response to DNA damage stimulus, cellular response to stress,

• 细胞定位：
• Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Mitochondrion. Accumulates in discrete nuclear foci prior to DNA damage, and these foci persist throughout the time course of DNA repair.

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